Baskin Lab Publications at Cornell:

3. Bumpus TW and Baskin JM. “Clickable Substrate Mimics Enable Imaging of Phospholipase D Activity.” ACS Cent Sci (2017). DOI: 10.1021/acscentsci.7b00222

Synopsis: Simple azidoalcohols enable a click chemistry-based method for imaging
the subcellular localizations of the active pools of phospholipase D signaling enzymes.

2. Knopf KM, Murphy BL, MacMillan SN, Baskin JM, Barr MP, Boros E, and Wilson JJ. “In Vitro Anticancer Activity and in Vivo Biodistribution of Rhenium(I) Tricarbonyl Aqua Complexes.” J Am Chem Soc (2017). DOI: 10.1021/jacs.7b08640

1. Bumpus TW and Baskin JM. “A Chemoenzymatic Strategy for Imaging Cellular Phosphatidic Acid Synthesis.” Angew Chem Int Ed, 55, 13155-58 (2016).

Jeremy’s Publications Prior to Cornell:

*Baskin JM, *Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM, De Camilli P. “The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.” Nat Cell Biol, 18, 132-38 (2016). Featured in Yale News and the Yale Daily News.

Chung J, Nakatsu F, Baskin JM, De Camilli P. “Plasticity of PI4KIIIα interactions at the plasma membrane.” EMBO Rep, 16, 312-20 (2015).

Wu X, Chi RJ, Baskin JM, Lucast L, Burd CG, De Camilli P, Reinisch KM. “Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.” Dev Cell, 28, 19–29 (2014). Featured in Faculty of 1000.

Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Sanders SJ, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N, State MW. “Rare deleterious mutations in the gene EFR3A are associated with autism spectrum disorders.” Mol Autism, 5, 31 (2014).

*Nakatsu F, *Baskin JM, Chung J, Tanner LB, Shui G, Lee SY, Pirruccello M, Hao M, Ingolia NT, Wenk MR, De Camilli P. “PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity.” J Cell Biol, 199, 1003–16 (2012). *Equal contribution. Featured in Faculty of 1000.

Dehnert KW, Baskin JM, Laughlin ST, Beahm BJ, Naidu NN, Amacher SL, Bertozzi CR. “Imaging the sialome during zebrafish development with copper-free click chemistry.” ChemBioChem, 13, 353–57 (2012).

Yao JZ, Uttamapinant C, Poloukhtine A, Baskin JM, Codelli JA, Sletten EM, Bertozzi CR, Popik VV, Ting AY. “Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition.” J Am Chem Soc, 134, 3720–28 (2012).

Dehnert KW, Beahm BJ, Huynh TT, Baskin JM, Laughlin ST, Wang W, Wu P, Amacher SL, Bertozzi CR. “Metabolic labeling of fucosylated glycans in developing zebrafish.” ACS Chem Biol, 6, 547–52 (2011).

*Baskin JM, *Dehnert KW, *Laughlin ST, Amacher SL, Bertozzi CR. “Visualizing enveloping layer glycans during zebrafish early embryogenesis.” Proc Natl Acad Sci USA, 107, 10360–65 (2010). Featured in Faculty of 1000. *Equal contribution.

Baskin JM and Bertozzi CR. “Copper-free click chemistry: Bioorthogonal reagents for tagging azides.” Aldrichimica Acta, 43, 15–23 (2010).

Beatty KE, Fisk JD, Smart BP, Lu YY, Szychowski J, Hangauer MJ, Baskin JM, Bertozzi CR, Tirrell DA. “Live-cell imaging of cellular proteins by a strain-promoted cycloaddition.” ChemBioChem, 11, 2092–95 (2010).

Chang PV, Prescher JA, Sletten EM, Baskin JM, Miller IA, Agard NJ, Lo A, Bertozzi CR. “Copper-free click chemistry in living animals.” Proc Natl Acad Sci USA, 107, 1821–26 (2010). Featured in Faculty of 1000.

Baskin JM and Bertozzi CR. “Copper-free click chemistry.” In Click Chemistry for Biotechnology and Materials Science. Ed. J. Lahann. pp. 25–51, Wiley (2009).

Nessen MA, Kramer G, Back J, Baskin JM, Smeenk LE, de Koning LJ, van Maarseveen JH, de Jong L, Bertozzi CR, Hiemstra H, de Koster CG. “Selective enrichment of azide-containing peptides from complex mixtures.” J Proteome Res, 8, 3702–11 (2009).

Hur GH, Meier JL, Baskin J, Codelli JA, Bertozzi CR, Marahiel MA, Burkart MD. “Crosslinking studies of protein-protein interaction in nonribosomal peptide biosynthesis.” Chem Biol, 16, 372–81 (2009).

*Laughlin ST, *Baskin JM, Amacher SL, Bertozzi CR. “In vivo imaging of membrane-associated glycans in developing zebrafish. Science, 320, 664–67 (2008). *Equal contribution. Featured in the New York Times, C&E News, Nat Chem Biol, Nat Reports Stem Cells, ACS Chem Biol, Science Daily, Chemistry World.

Johnson JA, Baskin JM, Bertozzi CR, Koberstein JT, Turro NJ. “Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers.” Chem Commun, 3064–66 (2008).

Codelli JA, Baskin JM, Agard NJ, Bertozzi CR. “Second-generation difluorinated cyclooctynes for copper-free click chemistry.” J Am Chem Soc, 130, 11486–93 (2008).

Baskin JM, Prescher JA, Laughlin ST, Agard NJ, Chang PV, Miller IA, Lo A, Codelli JA, Bertozzi CR. “Copper-free click chemistry for dynamic in vivo imaging.” Proc Natl Acad Sci USA, 104, 16793–97 (2007). Featured on the cover and in Nature, C&E News, Biophotonics InternationalScience Daily.

Baskin JM and Bertozzi CR. “Bioorthogonal click chemistry: Covalent labeling in living systems.” QSAR Comb Sci, 26, 1211–19 (2007).

Fernández-Suárez M, Baruah H, Martínez-Hernández L, Xie KT, Baskin JM, Bertozzi CR, Ting AY. “Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes.” Nat Biotechnol, 25, 1483–87 (2007).

*Agard NJ, *Baskin JM, Prescher JA, Lo A, Bertozzi CR. “A comparative study of bioorthogonal reactions with azides.” ACS Chem Biol, 1, 644–48 (2006). *Equal contribution. Featured on the cover and in Faculty of 1000.

Laughlin ST, Agard NJ, Baskin JM, Carrico IS, Chang PV, Ganguli AS, Hangauer MJ, Lo A, Prescher JA, Bertozzi CR. “Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics.” Methods Enzymol, 415, 230–50 (2006).

Antilla JC, Baskin JM, Barder TE, Buchwald SL. “Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles.” J Org Chem, 69, 5578–87 (2004).

Baskin JM and Wang Z. “An efficient copper catalyst for the formation of sulfones from sulfinic acid salts and aryl iodides.” Org Lett, 4, 4423–25 (2002).

Baskin JM and Wang Z. “A mild, convenient synthesis of sulfinic acid salts and sulfonamides from alkyl and aryl halides.” Tetrahedron Lett, 43, 8479–83 (2002).

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